{"id":47461,"date":"2024-02-14T19:21:50","date_gmt":"2024-02-14T13:51:50","guid":{"rendered":"https:\/\/gomedii.com\/blogs\/english\/?p=47461"},"modified":"2024-02-15T13:56:52","modified_gmt":"2024-02-15T08:26:52","slug":"indias-car-t-cell-therapy-with-dr-rahul-bhargava","status":"publish","type":"post","link":"https:\/\/gomedii.com\/blogs\/english\/health-a2z\/indias-car-t-cell-therapy-with-dr-rahul-bhargava\/","title":{"rendered":"Know About India&#8217;s CAR T-cell Therapy With Dr Rahul Bhargava | Fortis Hospitals"},"content":{"rendered":"<h1 style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">Know About India&#8217;s CAR T-cell Therapy With Dr Rahul Bhargava<\/span><\/h1>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">A short rendezvous with <a href=\"https:\/\/gomedii.com\/blogs\/english\/doctors-hospitals\/dr-rahul-bhargava-best-hematologist-in-gurugram\/\">Dr Rahul Bhargava<\/a>, Principal Director &amp; Chief BMT, <a href=\"https:\/\/gomedii.com\/india\/hospitals\/fortis-memorial-research-instutue-?lang=en\">Fortis Memorial Research Institute<\/a>, Gurugram, unraveled the mysteries of India&#8217;s CAR T-cell Therapy. NexCAR19, the indigenously developed CAR T-cell therapy, has revolutionized the way we view cancer treatment in India. Earlier, we would only talk about treating cancer by managing its symptoms. However, with rapid development in medical technology, India has shifted its focus to curing <a href=\"https:\/\/gomedii.com\/blogs\/english\/health-a2z\/nuances-in-cancer-management-with-dr-anil-thakwani\/\">cancer<\/a>. After a <a href=\"https:\/\/gomedii.com\/india\/treatments\/bone-marrow-transplant-treatment?lang=en\">bone marrow transplant<\/a> or <a href=\"https:\/\/gomedii.com\/blogs\/english\/treatments\/copd-stem-cell-therapy-cost-in-india\/\">stem<\/a> cell therapy, CAR T-cell therapy is here to take the game a notch higher.<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">Dr Rahul Bhargava shed light on NexCAR19, India&#8217;s CAR T-cell therapy indigenously developed by IIT Bombay and <a href=\"https:\/\/gomedii.com\/india\/hospitals\/tata-memorial-hospital-parel?lang=en\">TATA Memorial Hospital<\/a> in Mumbai (Bombay). Developing the country&#8217;s first CAR T-cell therapy was the brainchild of Dr. Alka Dwivedi and her team, who spent seven years researching and studying CAR T-cell therapies in the USA to develop a more humanized version for India. But why more humanized? This is so because Dr Dwivedi noticed that the CAR T-cell therapies being used in the USA contained antibody fragments derived from mice, which triggered severe side effects as a patient&#8217;s immune system rejected the foreign substance.<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">CAR T-cell therapy has proven to be highly effective against blood cancers like:<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span data-preserver-spaces=\"true\">Diffuse large B cell <a href=\"https:\/\/gomedii.com\/blogs\/english\/treatments\/gastric-lymphoma-treatment-cost-in-india\/\">lymphoma<\/a><\/span><\/li>\n<li><span data-preserver-spaces=\"true\"><a href=\"https:\/\/gomedii.com\/india\/treatments\/oncology_acute_leukemia_treatment?lang=en\">Acute<\/a> lymphoblastic <a href=\"https:\/\/gomedii.com\/blogs\/english\/treatments\/acute-myeloid-leukemia-treatment-cost-in-india\/\">leukemia<\/a> (ALL)<\/span><\/li>\n<li><a href=\"https:\/\/gomedii.com\/india\/treatments\/multiple-myeloma-treatment?lang=en\"><span data-preserver-spaces=\"true\">Multiple Myeloma<\/span><\/a><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<h2 style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">What Is CAR T-cell Therapy?<\/span><\/h2>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">Dr Bhargava excitingly explained the concept. T-cells are a type of white blood cell called lymphocytes. They help your immune system fight germs and protect you from disease. To help you understand better, think of them as your body&#8217;s security guards who stop and kill foreign elements like <a href=\"https:\/\/gomedii.com\/blogs\/english\/health-a2z\/staphylococcus-aureus-bacteria-treatment-in-india\/\">bacteria<\/a> or <a href=\"https:\/\/gomedii.com\/blogs\/english\/international-health-news\/two-coronaviruses-suspect-under-watch-in-mumbai\/\">viruses<\/a> entering your body.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">But these cells need to function normally as hyperactive T-cells can lead to <a href=\"https:\/\/gomedii.com\/blogs\/english\/health-a2z\/diabetes-lada\/\">autoimmune<\/a> disorders. On the other hand, exhausted or dysfunctional T-cells can lead to the growth of cancer in your body.<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">India&#8217;s CAR T-cell therapy, also called Chimeric Antigen T-cell therapy, is a type of <a href=\"https:\/\/gomedii.com\/blogs\/english\/doctors-hospitals\/immunotherapy-cost-in-chennai\/\">immunotherapy<\/a> where your T-cells are genetically modified in a lab to fight cancer. It is one of the precision therapies as, unlike <a href=\"https:\/\/gomedii.com\/india\/treatments\/chemoradiotherapy?lang=en\">chemotherapy<\/a>, it only targets the cancer cells, leaving the healthy cells intact.<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">The CAR T-cell therapy was first envisioned in the USA in 2010. It was given to 10,000 US cancer patients, out of which the condition of at least 100 patients was severe. Post trials, 60% of the participants showed no signs of cancer after completion of the treatment, but quite a few participants showed neurologic side effects.<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">How Is CAR T-cell Therapy Done?<\/span><\/h3>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">Dr Bhargava also explained the whole procedure in simple steps. The procedure is similar to a bone marrow transplant with minor changes. Firstly, your T-cells are collected and isolated in a lab. Then, they are genetically engineered by introducing DNA into them to produce chimeric antigen receptors (CARs) on the surface of the cells. The patient is put in remission mode by giving chemotherapy, after which the CAR T-cells are infused into the body via a catheter.<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<h4 style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">What Makes India&#8217;s CAR T-cell Therapy Preferable?<\/span><\/h4>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">India&#8217;s CAR T-cell Therapy is highly preferable over the ones available in the USA because:<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><strong><span data-preserver-spaces=\"true\">Affordability:<\/span><\/strong><span data-preserver-spaces=\"true\">\u00a0CAR T-cell therapy in the USA costs around\u00a0<\/span><strong><span data-preserver-spaces=\"true\">INR 3 crore to INR 4 crore (USD 361,330 to USD 481,773)<\/span><\/strong><span data-preserver-spaces=\"true\">, whereas India&#8217;s CAR T-cell therapy is one-eighth times cheaper at <\/span><strong><span data-preserver-spaces=\"true\">INR 40 Lakhs to INR 50 Lakhs (USD 48,177 to USD 60,221).<\/span><\/strong><\/li>\n<li><strong><span data-preserver-spaces=\"true\">Effectiveness:<\/span><\/strong><span data-preserver-spaces=\"true\">\u00a0The success rate of CAR T-cell therapy in India is\u00a0<\/span><strong><span data-preserver-spaces=\"true\">65-70%<\/span><\/strong><span data-preserver-spaces=\"true\">. The treatment is effective even in the later stages of cancer.<\/span><\/li>\n<li><strong><span data-preserver-spaces=\"true\">Reduced side-effects:<\/span><\/strong><span data-preserver-spaces=\"true\">\u00a0The side-effects of CAR T-cell therapy in India are much less compared to the ones available in the USA due to the use of more human-like antigens.<\/span><\/li>\n<li><strong><span data-preserver-spaces=\"true\">Adherence to standards:<\/span><\/strong><span data-preserver-spaces=\"true\">\u00a0India&#8217;s CAR T-cell Therapy meets all significant international healthcare standards.<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">What Is The Future Of CAR T-cell Therapy In India?<\/span><\/h3>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">Dr Bhargava states that India&#8217;s CAR T-cell therapy has a bright future. With time, new players will enter this market, ending the monopoly. A biopharma ecosystem will be created to make the therapy more accessible for both domestic and international patients. Companies like Immuneel Therapeutics and Dr. Reddys have already started offering CAR T-cell therapies.<\/span><\/p>\n<p>&nbsp;<\/p>\n<div>\n<div class=\"rAzITb PZPZlf k0Jjg fCrZyc NQYJvc FR7ZSc eFSWxd gzV1t\" tabindex=\"0\" role=\"button\" data-key=\"What is the cost of hemolytic anemia?\" data-hveid=\"CBIQBQ\" data-ved=\"2ahUKEwjf4qiuuaiEAxWQ7jgGHd7LDIIQ998KKAJ6BAgSEAU\">\n<div class=\"niO4u\">\n<div>\n<h3 style=\"text-align: center;\"><span data-preserver-spaces=\"true\">Choose GoMedii For The Best And Affordable CAR T-cell Therapy Cost In India<\/span><\/h3>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">If you want the best and most affordable CAR T-cell Therapy cost in India, you are at the right place and time! Trust GoMedii, the <\/span><a class=\"editor-rtfLink\" href=\"https:\/\/gomedii.com\/india\/medical\/tourism-company-in-india?lang=en\" target=\"_blank\" rel=\"noopener\"><span data-preserver-spaces=\"true\">best medical tourism company in India<\/span><\/a><span data-preserver-spaces=\"true\">, with your treatment; we assure you of a top-notch, hassle-free process.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify;\"><span data-preserver-spaces=\"true\">We have tie-ups with one of the most reputed hospitals to get you the\u00a0<\/span><a class=\"editor-rtfLink\" href=\"https:\/\/gomedii.com\/india\/?lang=en\" target=\"_blank\" rel=\"noopener\"><span data-preserver-spaces=\"true\">best medical treatment in India<\/span><\/a><span data-preserver-spaces=\"true\">\u00a0at an affordable cost. Furthermore, to avail yourself of our packages, you can contact us on our website or at\u00a0<\/span><strong><span data-preserver-spaces=\"true\">+91-9599004311<\/span><\/strong><span data-preserver-spaces=\"true\">. Additionally, you can also email us at\u00a0<\/span><strong><span data-preserver-spaces=\"true\">connect@gomedii.com<\/span><\/strong><span data-preserver-spaces=\"true\">. Our team will respond to you on a priority basis.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a class=\"editor-rtfLink\" href=\"https:\/\/gomedii.com\/india\/info\/contactus?lang=en\" target=\"_blank\" rel=\"noopener noreferrer\"><span data-preserver-spaces=\"true\">Contact GoMedii<\/span><\/a><span data-preserver-spaces=\"true\">\u00a0to get your queries resolved by our team of medical experts. You can also reach out to us to\u00a0<\/span><a class=\"editor-rtfLink\" href=\"https:\/\/gomedii.com\/india\/assessments\/medical-visa?lang=en\" target=\"_blank\" rel=\"noopener noreferrer\"><span data-preserver-spaces=\"true\">apply for a medical visa<\/span><\/a><span data-preserver-spaces=\"true\">.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<div>\n<div class=\"rAzITb PZPZlf k0Jjg fCrZyc NQYJvc FR7ZSc eFSWxd gzV1t\" tabindex=\"0\" role=\"button\" data-key=\"What is the cost of hemolytic anemia?\" data-hveid=\"CBIQBQ\" data-ved=\"2ahUKEwjf4qiuuaiEAxWQ7jgGHd7LDIIQ998KKAJ6BAgSEAU\">\n<div class=\"niO4u\">\n<div>\n<p style=\"text-align: justify;\"><strong><span data-preserver-spaces=\"true\">Book Your Appointment With Us Today!\u00a0<\/span><\/strong><span data-preserver-spaces=\"true\">\u00a0[su_button url=\u201dhttps:\/\/wa.me\/919599004311\u2033 target=\u201dblank\u201d style=\u201dstroked\u201d background=\u201d#2def2f\u201d size=\u201d4\u2033 icon=\u201dicon: WhatsApp\u201d]WhatsApp Now[\/su_button]<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Know About India&#8217;s CAR T-cell Therapy With Dr Rahul Bhargava \u00a0 A short rendezvous with Dr Rahul Bhargava, Principal Director &amp; Chief BMT, Fortis Memorial Research Institute, Gurugram, unraveled the mysteries of India&#8217;s CAR T-cell Therapy. NexCAR19, the indigenously developed CAR T-cell therapy, has revolutionized the way we view cancer treatment in India. Earlier, we&nbsp;<\/p>\n<p><a class=\"btn btn-style\" href=\"https:\/\/gomedii.com\/blogs\/english\/health-a2z\/indias-car-t-cell-therapy-with-dr-rahul-bhargava\/\">Continue Reading<\/a><\/p>\n","protected":false},"author":43,"featured_media":47476,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[63711,63707,63710,63709,63697,63696,63708,63703,63704,63698,63700,63701,63702,63699,63705,63706],"yst_prominent_words":[13336,1263],"_links":{"self":[{"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/posts\/47461"}],"collection":[{"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/users\/43"}],"replies":[{"embeddable":true,"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/comments?post=47461"}],"version-history":[{"count":10,"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/posts\/47461\/revisions"}],"predecessor-version":[{"id":47482,"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/posts\/47461\/revisions\/47482"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/media\/47476"}],"wp:attachment":[{"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/media?parent=47461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/categories?post=47461"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/tags?post=47461"},{"taxonomy":"yst_prominent_words","embeddable":true,"href":"https:\/\/gomedii.com\/blogs\/english\/wp-json\/wp\/v2\/yst_prominent_words?post=47461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}