Cushing syndrome is a medical condition where the body produces too much cortisol for an extended time. Also called hypercortisolism, cortisol produced by the body can lead to many complications like high blood pressure or bone loss. Cortisol is also known as stress hormone as it helps your body to respond to stress. Cortisol also helps in maintaining blood pressure, reduces inflammation, and regulate glucose level in the blood.
Cortisol is produced by adrenal glands, two small glands that are present above the kidneys.
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Cushing Syndrome Causes
There are various causes of Cushing syndrome, such as:
- Use of glucocorticoid medications.
- Pituitary tumours. Eight out of ten cases of Cushing syndrome, excluding those caused by iatrogenic Cushing syndrome, are caused by pituitary tumours that produce excessive amounts of ACTH. This hormone instructs the adrenal glands to produce cortisol.
- Adrenal cortical tumours.
- Lung, pancreas, thyroid and thymus tumours.
Cushing Syndrome Signs And Symptoms
There are many symptoms of Cushing syndrome, but not all are exhibited by the patient simultaneously. Each person afflicted with Cushing syndrome exhibits a unique set of symptoms. The symptoms are:
- Rapid weight gain in the abdomen, back of the neck (sometimes called “buffalo hump”) and chest.
- A red, round face (moon face).
- Wounds that heal poorly.
- High blood pressure (hypertension).
- Excessive hair growth on the face, neck, chest, abdomen, breasts and thighs, or balding.
- Diabetes.
- Increased fat around the base of the neck.
Other signs and symptoms of Cushing syndrome include:
- Wide, purple stretch marks mainly on the abdomen, breasts, hips and under the arms.
- Easy bruising on the arms and legs.
- General weakness and tiredness (fatigue).
- Blurry vision and dizziness.
- Weak muscles and thinner arms and legs.
- Libido changes (sex drive) and erectile dysfunction.
- Stunted growth in children.
Cushing Syndrome Complications
Without treatment, Cushing syndrome can cause complications, including:
- Bone loss, also called osteoporosis, which can lead to broken bones.
- High blood pressure is also called hypertension.
- Type 2 diabetes.
- Severe or multiple infections.
- Loss of muscle mass and strength.
- Increases risk of stroke and/or heart attack.
- Depression.
Diagnosis Of Cushing Syndrome
Your healthcare provider will first discuss your health and medical history. They might conduct a physical examination and some lab tests as well. Your endocrinologist can also look at all your medicines — pills, injections, creams and inhalers — to see if you’re taking medicines that can cause the syndrome. If you are, you won’t need other tests.
Sometimes it can be challenging to identify Cushing syndrome. They might not instantly consider Cushing syndrome if you mention weariness and weight increase to your healthcare physician. Many different sorts of diseases have these kinds of symptoms.
The diagnostic tests for Cushing syndrome are:
- 24-hour urinary free-cortisol test: Your doctor collects your urine over 24 hours to check the level of cortisol in it.
- Midnight salivary cortisol test: Your healthcare provider will collect your saliva between 11:00 pm – 12:00 am to check your cortisol level. Higher levels will likely indicate Cushing syndrome.
- Low-dose dexamethasone suppression test: Your healthcare provider will ask you to take a low dose of the dexamethasone drug at night to test for cortisol in the morning. If you have Cushing syndrome, your cortisol levels will remain high.
- Blood tests: A blood test will determine your ACTH levels. If the levels are low, an adrenal tumour could be present. A pituitary or ectopic tumour may exist if the readings are normal or elevated.
- High-dose dexamethasone suppression test is the same as the low-dose dexamethasone suppression test. The only difference is the dose of the drug is high in this case. This test can determine the source of Cushing syndrome.
- Inferior petrosal sinus sampling: This test can help establish whether Cushing syndrome is caused by an ACTH-producing pituitary adenoma or another organ’s ACTH-producing tumour.
- Imaging tests: CT or MRI scans can take pictures of the pituitary and adrenal glands to see if anything, such as tumours, shows up.
Cushing Syndrome Treatment In India
The treatment of Cushing syndrome depends on its cause. If you use glucocorticoids, your healthcare provider will likely lower the dosage or prescribe a non-glucocorticoid medication. If a tumour’s causing Cushing syndrome, your provider may suggest surgery or radiation. Various available treatments are:
- Medications: Your endocrinologist might ask you to stop taking glucocorticoids or give you medications to slow down the production of cortisol in your body.
- Radiation therapy: It may be given if Cushing syndrome is not treated by surgery. But, cortisol levels can take years to return to normal.
- Chemotherapy: If the tumour is cancerous (in the case of Lung, pancreas, thyroid and thymus tumours) and has become malignant, chemotherapy may be required.
- Surgery: Surgically removing pituitary tumours, adrenal tumours, and ectopic tumours is effective, but you’ll have to adjust to new, lower cortisol levels.
Cushing Syndrome Treatment Cost In India
Depending on the type of treatment chosen, the cost of cushing syndrome treatment in India ranges between $600 to $5000.
Cushing Syndrome Treatment Hospitals In India
GoMedii has compiled the best hospitals for your Cushing syndrome treatment in India. These hospitals house one of India’s best endocrinology teams and state-of-art medical facilities, giving you personalized treatment.
The top 19 Cushing syndrome treatment hospitals are:
- Apollo Hospitals, Bannerghatta, Bangalore
- Lilavati Hospital and Research Centre, Mumbai, Maharashtra
- Medanta the Medicity, Gurugram
- Max Super Specialty Hospital, Saket, Delhi
- Gleneagles Global Hospital, Hyderabad, Telangana
- Care Institute of Medical Sciences, Ahmedabad
- BLK Super Specialty Hospital, Delhi
- Indraprastha Apollo Hospital, New Delhi
- Jaypee Hospital, Noida
- Fortis Hospital, Bangalore
- Nanavati Super Specialty Hospital, Mumbai
- Batra Hospital and Medical Research Centre, Delhi
- Fortis Hospital, Ahmedabad
- Venkateshwar Hospital, Delhi
- Fortis Escorts Hospital, Amritsar
- SCI International Hospital, Delhi
- Fortis La Femme, Delhi
- Sharda Hospital, Greater Noida
- Fortis Escorts Hospital, Faridabad
FAQs On Cushing Syndrome Treatment In India
1. What are the two causes of Cushing syndrome?
Cushing’s syndrome (CS) is a medical condition caused by the adrenal gland(s) making too much of a hormone called cortisol. CS is most often due to a tumour or mass found in the pituitary gland, but it can also be caused by tumours in the adrenal glands themselves.
2. How long after stopping steroids does Cushing’s go away?
Slowly tapering the medicine causing the condition can help reverse the effects of adrenal gland shrinkage (atrophy). This may take months to as long as a year.
3. What is the best diet for Cushing syndrome?
The Cushing Syndrome Diet emphasizes protein-rich foods, which can be obtained by eating green vegetables, tofu, cottage cheese, salmon, yoghurt, and beans. Higher cortisol levels raise blood sugar levels, leading to diabetes if not appropriately managed.
4. What is the cost of Cushing syndrome treatment in India?
Depending on the type of treatment chosen, the cost of crushing syndrome treatment in India ranges between $600 to $5000.
5. What is the difference between Cushing’s syndrome and Cushing’s disease?
Cushing disease is a subtype of Cushing syndrome. It happens when a pituitary tumour causes the body to produce too much cortisol. Cushing disease is the most frequent form of endogenous (from the body) Cushing syndrome, accounting for around 70% of Cushing syndrome patients.
Choose GoMedii for the Affordable Cushing Syndrome Treatment in India
If you want affordable Cushing syndrome treatment in India, you are at the right place and time! Trust GoMedii with your treatment; we assure you of a top-notch, hassle-free process.
We have tie-ups with one of India’s most reputed hospitals to get you the best treatment at an affordable cost. Furthermore, to avail of our packages, you can contact us on our Website and call us at +91-9599004311. Additionally, you can also email us at connect@gomedii.com. Our team will respond to you on a priority basis.
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