Know The Symptoms And Causes of Crouzon Syndrome!

Shikhar Atri

, Health A2Z

It is a rare genetic disorder in baby’s there are many of the flexible seams in a baby’s skull that turn to bone and fuse too early. Why this happens, so we will tell you the causes of crouzon syndrome. The early fusion of the baby skull is the hallmark of a group of conditions called craniosynostoses.

 

(People Also Like To Read: Symptoms Of Moebius Syndrome, Know What It Is)

 

Generally, sutures in a baby’s skull are stayed open to let the brain grow. But when these sutures close too early and the baby’s brain keeps growing, then the baby’s skull and face can become misshapen.

 

Causes of Crouzon Syndrome

 

Causes of Crouzon Syndrome, craniosynostoses, Crouzon Syndrome, FGFR genes, autosomal dominant, Treatment For Crouzon Syndrome, Expectancy

 

The crouzon syndrome happens by the mutations in one of the four FGFR genes. Generally, it affects the FGFR2 gene, and also less often the FGFR3 gene. Your Genes carry the instructions for making the proteins that direct your body’s functions and the Mutations can affect whatever functions a specific protein has. The full form of FGFR is the fibroblast growth factor receptor. The FGFR2 codes for a protein called fibroblast growth factor receptor 2.

 

When a baby develops in the womb, then this protein signals bone cells to form. When it comes to Mutations, so this gene amp up the signal, increasing bone development and causing the baby’s skull to fuse too soon.

 

According to the experts, a baby only needs to inherit one copy of the gene mutation from a parent to get Crouzon syndrome. In case, you have this condition, each of your children has a fifty-fifty chance of inheriting it. Then this inheritance pattern is called autosomal dominant.

 

Till now, about 25 to 50 percent of people with Crouzon syndrome, the mutation of gene happens spontaneously. In that cases, babies do not need to have a parent with Crouzon syndrome to get the disorder.

 

(You Might Also Like To Read: 5 Questions Of Mood Disorder Questionnaire, Important)

 

Symptoms Of Crouzon Syndrome

 

The symptoms of crouzon syndrome include:

 

  • Enlarged forehead

 

  • Short and wide or long and narrow head

 

  • Bulging eyeballs

 

 

  • Widely spaced eyes (Difference in both eyes)

 

  • Crossed eyes (strabismus)

 

  • Baby’s eyes in two different directions

 

  • Eyelids that slant downward

 

  • Flattered cheeks

 

  • Curved, beak-like nose

 

  • Short upper lip

 

  • The small, poorly developed upper jaw

 

 

  • Crowded teeth

 

  • Lower jaw protruding

 

Sometimes symptoms may be more severe in babies than in others. We told the causes of crouzon syndrome then we will also tell you what’s the available treatment.

 

How it is Diagnosed?

 

Causes of Crouzon Syndrome, craniosynostoses, Crouzon Syndrome, FGFR genes, autosomal dominant, Treatment For Crouzon Syndrome, Expectancy

 

To diagnose the crouzon syndrome doctor will usually examining the patient. In some cases, genetic testing is also done to confirm the diagnosis. The doctor may also suggest for X-ray, MRI, and CT scan.

 

Treatment For Crouzon Syndrome

 

Those children have mild crouzon syndrome then they do not need treatment. But in more severe cases children’s parents have should see craniofacial specialists, doctors who treat disorders of the skull and face.

 

When there is a more severe case, then the doctors perform surgery to open up the sutures and give the brain room to grow. Once the surgery, the doctor recommends to kids will need to wear a special helmet for a few months to reshape their skull.

 

Surgery can also be done to:

 

  • Fix a cleft lip or palate

 

  • Relieve pressure inside the skull

 

  • Correct eye problems with surgery

 

  • Correct a malformed jaw

 

  • Straighten crooked teeth

 

  • Kids with hearing problems can wear hearing aids to amplify the sound

 

  • In some kids with this condition may also need speech and language therapy

 

Crouzon syndrome can be detected before birth?

 

Causes of Crouzon Syndrome, craniosynostoses, Crouzon Syndrome, FGFR genes, autosomal dominant, Treatment For Crouzon Syndrome, Expectancy

 

After you know the causes of Crouzon syndrome. Parents asked this question. It cannot be detected before birth. Till now it is diagnosed at birth, based on the appearance of your child’s face and skull.

 

What is the Life Expectancy?

 

Children with Crouzon syndrome have a normal life expectancy. In most cases, children with this condition are unaffected intellectually. Still, it can alter the shape of the face and cause vision and hearing problems.

 

Conclusion

 

When we are talking about how rare it is. It is estimated to affect about 1.6 in 100,000 people in the general population. In case your kid has Crouzon syndrome then treatment is also available, you don’t need to worry about it.

 

(People Also Like To Read: 7 Tips for Mindful Eating, You Should Try!)


Disclaimer: GoMedii is a recognized and a considerate healthcare platform which tends to connect every dot of the healthcare needs and facilities. GoMedii facilitates the accessibility of all health news, health tips, and information from the Health experts and Doctors to the eyes of readers. All of the information and facts mentioned in the GoMedii Blog are thoroughly examined and verified by the Doctors and Health Experts, elsewise source of information is confirmed for the same.


 About GoMedii: GoMedii is a Healthcare Technology Platform That Works Out Your Treatment / Surgery the Way You Need & Plan. A Treatment partner that simplifies the patient journey at every step. Drop Your Queries for the most affordable & world-class treatment options.You may simply download the GoMedii app for Android or iOS.