Pheochromocytoma Surgery Cost in India

Kanchan Kashyap

, Health A2Z

For your medical requirements, we have well-equipped facilities and a fully operational advanced-care general surgery unit, which is inclusive of the cost of Pheochromocytoma Surgery in India. With modern medical equipment and facilities, the patients are offered a comprehensive, experienced, and most importantly, modern service all in one place.

The case of pheochromocytoma is a complex clinical state that demands the use of numerous drugs, assessment of various signs, and specific diagnosing procedures. Clinicians or medical practitioners require expertise in the array of factors connected with this rare condition to enhance patient management choices. The long-term advantage of it will be improved patient health and improved quality of life.

When adrenal glands are mentioned this can mean that they may develop pheochromocytomas, which are relatively rare cancer growths. These tumors are usually non-cancerous, (benign); however, due to the overproduction of both adrenaline and noradrenaline, severe health complications arise. These hormones control the body’s reaction to stress and impact pulse rates, blood pressure, biochemical workings, etc. Some symptoms of pheochromocytoma are detailed below:

 

Symptoms

When dealing with pheochromocytoma, individual variances and uncommon cases of no symptoms are possible. However, the following symptoms are frequently present with pheochromocytoma:

  • Rapid heartbeat
  • Weight loss
  • Headaches
  • Palpitations
  • Sweating
  • Abdominal pain
  • High blood pressure
  • Tremors

Complications

  • The disease of your heart muscle (cardiomyopathy)
  • Stroke
  • Nerve damage in the eyes
  • Kidney failure
  • Pulmonary edema
  • Heart attack
  • Bleeding in the brain
  • Heart muscle inflammation (myocarditis)

 

Risk Factors for Pheochromocytoma Surgery

Pheochromocytoma patients may be more susceptible to more severe forms of the illness. These hereditary disorders comprise the following:

  • Hereditary paraganglioma syndrome.
  • There are several types of thyroid cancer, and only one of those multiple endocrine neoplasias type II (MEN2) is associated with pheochromocytoma.
  • Skin cancer and optic nerve tumor are the symptoms of neurofibromatosis type 1 (NF1).
  • In VHL, nearly all of the cysts and tumors are benign and mainly arise in the adrenal gland, kidneys, CNS, and o ther sites.

 

Diagnosis for Pheochromocytoma Surgery

The medical team uses imaging and biochemical and clinical investigations in the diagnosis of pheochromocytoma. Below is a detailed explanation of the diagnostic process:

  1. Biochemical testing:

Plasma or urine containing normetanephrine and metanephrines – those are breakdown products of catechol amine. Therefore, pheochromocytoma should also be suspected if the levels of normetanephrine and metanephrines are high in blood or urine. The results make plasma-free metanephrines and 24-h urine collection coordinating standard of care.

Catecholamine– diagnostic tools include the determination of catecholamines in blood or urine that include noradrenaline and adrenaline.

  1. Genetic Testing:

If a hereditary syndrome is identified, genetic testing can identify mutations connected to diseases such as MEN 2 or VHL.

  1. Functional Localization

Selective Venous Sampling– This technique can be applied in situations where imaging data are ambiguous or nonexistent. Since the body is attempting to determine why the production of catecholamines is up, blood from many veins needs to be taken.

Octreotide Scintigraphy – This is a nuclear medicine imaging procedure that involves the use of a radioactive substance, which is attached to certain tumours, including pheochromocytomas.

  1. A clinical assessment

Medical History– due to the rarity in the differentiation of the symptoms of pheochromocytoma from the symptoms of other infections, a detailed Medical history needs to be taken. Some of the possible symptoms are Headaches and High Blood Pressure, Sweating and Palpitations, Panic Attacks, and others.

Historical Background– Pheochromocytoma has been associated with several genetic disorders, including Von Hippel-Lindau (VHL) syndrome and multiple endocrine neoplasia type 2 (MEN 2). A certain syndrome may raise suspicions if it runs in the family.

  1. Provocative Testing:

Certain individuals may be subjected to provocative testing, such as the clonidine suppression test or the glucagon stimulation test to elicit catecholamine release and establish a diagnosis. It’s important to emphasize that every person has a unique diagnosing procedure. Depending on the patient’s unique symptoms and situation, the medical staff will modify their strategy. Surgical excision is usually required upon tumor detection. This is where to begin managing the sickness and preventing complications.

  1. Imaging tests:

MRI or CT scan– if there are suspicions of tumours and to define their extent, an MRI or a CT scan may need to be carried out. For the abdomen/pelvis, a contrast-enhanced Computed Tomography (CT) or scan is usually done, or Magnetic Resonance Imaging. Pheochromocytoma usually presents as solid nodules that are distinct.

MIBG Scintigraphy– pheochromocytomas containing tumors are among those that absorb the radioactive substance Metaiodobenzylguanidine (MIBG). In MIBG scintigraphy, the tumor regions are scanned after a tiny amount of radioactive MIBG is injected.

PET Scan– Pheochromocytoma can also be found with PET scans, which use certain tracers.

 

Pheochromocytoma Surgery

To remove the tumor, pheochromocytoma cases usually require surgery, either an open laparotomy or a laparoscopy. Before Pheochromocytoma Surgery, your doctor will prescribe and deliver several medications to help control your blood pressure and pulse. This is done at the hospital so that your vital signs may be closely monitored by the physician. After the procedure, your physician will admit you to the intensive care unit (ICU) so they can keep a close eye on your vital signs. Surgery may be required to treat the situation, in particular, an adrenalectomy, which is the removal of injured adrenal glands.

The process of Pheochromocytoma Surgery is somewhat lengthy and cumbersome, and given the potential for mishaps, it is advised that the treatment be given under the supervision of medical professionals, who are commonly found in hospitals that deal with such diseases. These will be medical facilities with all the required stocks, anesthetics, and hormones will be used.

Specific drugs must be administered for managing a patient’s blood pressure before surgical interventions; the most suitable of them is phenoxybenzamine, which is a short active alpha antagonist as well as an irreversible and nonselective alpha-adrenoceptor blocker. This minimizes the chances of a marked intraoperative hypertension manifesting itself in the course of the Pheochromocytoma Surgery process.

Patients with pheochromocytoma frequently have volume deficits. This indicates a large reduction in urine volume due to almost total inhibition of renin-angiotensin action, which results in a drop in blood volume. There is likely volume depletion and low sympathetic activity after resection of pheochromocytoma, hypotension is a dangerous issue in this case. As a result, persons with pheochromocytoma are encouraged to “salt load” before surgery. Your doctor will recommend foods with high quantities of sodium before the surgery. The two other methods to “salt load” are intravenous saline solution injection and direct salt replacement.

 

Pheochromocytoma Surgery Cost in USD in India

One or both of the adrenal glands may be surgically removed in a process called adrenalectomy. A simple adrenalectomy implies that only one adrenal gland is removed while a bilateral adrenalectomy means that both adrenals are removed. The standard procedure for pheochromocytoma removal is adrenalectomy. If the cancer has spread, these tissues could require to be removed. This treatment will involve some scrutiny of the tissues and lymph nodes in the abdomen.

 

Treatment Laparoscopic Adrenalectomy
Success Rate 95-99%
Approx. Treatment Cost 4500 USD
Total Stay in Hospital 1-2 weeks
Total Stay in India 16-21 days

 

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